JPS5754151A - Physiologically active substance b-52653 and its preparation - Google Patents
Physiologically active substance b-52653 and its preparationInfo
- Publication number
- JPS5754151A JPS5754151A JP55130298A JP13029880A JPS5754151A JP S5754151 A JPS5754151 A JP S5754151A JP 55130298 A JP55130298 A JP 55130298A JP 13029880 A JP13029880 A JP 13029880A JP S5754151 A JPS5754151 A JP S5754151A
- Authority
- JP
- Japan
- Prior art keywords
- physiologically active
- active substance
- substance
- gram
- positive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013543 active substance Substances 0.000 title abstract 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 230000001747 exhibiting effect Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 abstract 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 1
- 241000187747 Streptomyces Species 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 238000000921 elemental analysis Methods 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-ZSJDYOACSA-N heavy water Substances [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 abstract 1
- 230000004260 plant-type cell wall biogenesis Effects 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/887—Streptomyces albus
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55130298A JPS5754151A (en) | 1980-09-18 | 1980-09-18 | Physiologically active substance b-52653 and its preparation |
US06/300,285 US4575489A (en) | 1980-09-18 | 1981-09-08 | Streptomyces albulus subsp. ochragerus subsp. nov. culture for making peptide |
DE19813136675 DE3136675A1 (de) | 1980-09-18 | 1981-09-16 | Neues peptid und dessen herstellung |
GB8128160A GB2084158B (en) | 1980-09-18 | 1981-09-17 | Peptide and production thereof |
FR8117581A FR2490223B1 (fr) | 1980-09-18 | 1981-09-17 | Nouveau peptide, son procede de preparation et culture du microorganisme utilise dans ce procede |
US06/629,499 US4623733A (en) | 1980-09-18 | 1984-07-10 | Antimicrobial peptide |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55130298A JPS5754151A (en) | 1980-09-18 | 1980-09-18 | Physiologically active substance b-52653 and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5754151A true JPS5754151A (en) | 1982-03-31 |
JPH0147479B2 JPH0147479B2 (en]) | 1989-10-13 |
Family
ID=15030963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55130298A Granted JPS5754151A (en) | 1980-09-18 | 1980-09-18 | Physiologically active substance b-52653 and its preparation |
Country Status (5)
Country | Link |
---|---|
US (2) | US4575489A (en]) |
JP (1) | JPS5754151A (en]) |
DE (1) | DE3136675A1 (en]) |
FR (1) | FR2490223B1 (en]) |
GB (1) | GB2084158B (en]) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57123155A (en) * | 1981-01-26 | 1982-07-31 | Takeda Chem Ind Ltd | Preparation of pyrrolidine derivative and its intermediate |
ZA832844B (en) * | 1982-05-18 | 1984-03-28 | Smithkline Beckman Corp | Oligopeptide prodrugs |
JPH0672893B2 (ja) * | 1985-08-16 | 1994-09-14 | 富士薬品工業株式会社 | ヒト血中のヒトプロリルヒドロキシラーゼの放射性免疫学的測定法による定量法 |
US4980283A (en) * | 1987-10-01 | 1990-12-25 | Merck & Co., Inc. | Renin-inhibitory pepstatin phenyl derivatives |
DE3930696A1 (de) * | 1989-09-14 | 1991-03-28 | Hoechst Ag | Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel |
GB0206711D0 (en) * | 2002-03-21 | 2002-05-01 | Isis Innovation | HIF Inhibitor |
US20100150985A1 (en) * | 2008-04-24 | 2010-06-17 | George Just | Dental Implant, Endodontic Instrument, and Dental Filling Material Coated with a Peptide-Based Antimicrobial and Methods of Using and Making the Same |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3077478A (en) | 1960-05-09 | 1963-02-12 | Rohm & Haas | 5-hydrocarbon-amino-2-pyrrolidinones and piperidones |
US3317559A (en) | 1963-08-23 | 1967-05-02 | American Cyanamid Co | alpha-amino acid esters of n-hydroxysuccinimide and preparation and use in peptide synthesis |
US4355112A (en) * | 1977-06-06 | 1982-10-19 | Sanraku-Ocean Co., Ltd. | Streptomyces culture |
JPS57123155A (en) | 1981-01-26 | 1982-07-31 | Takeda Chem Ind Ltd | Preparation of pyrrolidine derivative and its intermediate |
-
1980
- 1980-09-18 JP JP55130298A patent/JPS5754151A/ja active Granted
-
1981
- 1981-09-08 US US06/300,285 patent/US4575489A/en not_active Expired - Fee Related
- 1981-09-16 DE DE19813136675 patent/DE3136675A1/de not_active Withdrawn
- 1981-09-17 FR FR8117581A patent/FR2490223B1/fr not_active Expired
- 1981-09-17 GB GB8128160A patent/GB2084158B/en not_active Expired
-
1984
- 1984-07-10 US US06/629,499 patent/US4623733A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US4623733A (en) | 1986-11-18 |
US4575489A (en) | 1986-03-11 |
DE3136675A1 (de) | 1982-05-06 |
FR2490223A1 (fr) | 1982-03-19 |
GB2084158A (en) | 1982-04-07 |
GB2084158B (en) | 1984-05-31 |
FR2490223B1 (fr) | 1985-06-14 |
JPH0147479B2 (en]) | 1989-10-13 |
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